Health Article: Nutrient Protection for Healthy Eyes and Vision

Nutrient Protection for Healthy Eyes and Vision*
Juniper Devecis MS RD CCN, Biochemist for Pure Encapsulations

The eye is a complex organ whose very mechanism involves being exposed to large amounts of sunlight and other environmental antagonists. Antioxidants and carotenoids help to filter light and promote antioxidant defenses. Essential fatty acids are also protective, and offer support for healthy inflammatory balance and moisture retention in the eye.*

The importance of nutrients for eye health has been particularly evident since the publication of a long-term, multi-center, prospective study involving more than 5,000 individuals ages 55-80. Results revealed that high amounts of vitamin C, vitamin E, zinc and copper support the health of the macula.1 Similar results have been found with higher serum vitamin D levels and omega-3 essential fatty acids.2,3*

Lutein and zeaxanthin are the two major carotenoid pigments in the human macula and retina. These carotenoids act in the eye as macular pigments, helping to support the integrity and density of the macula lutea. Research indicates that they also provide antioxidant defense to protect the ocular tissue and promote gap junction communications, resulting in improved retinal signal efficiency. Multiple clinical studies suggest a direct relationship between lutein supplementation and macula lutein concentration. Higher intakes of these carotenoids promote macular and optic lens health, and offer visual acuity support.4,5 In a 12-month, randomized, double-blind, placebo-controlled trial involving 90 subjects, 10 mg of lutein was found to promote visual function both alone and when combined with a multivitamin.6 Studies suggest that this support is also due in part to the carotenoid's ability to filter high-energy blue wavelengths of light, thus minimizing retinal glare.*

Omega-3 essential fatty acids also offer support for eye hydration and comfort. In a 10-year, randomized, double-blind, placebo-controlled study involving nearly 40,000 women, higher intake of omega-3 fatty acids was associated with retention of eye moisture.7 Research suggests that these essential fatty acids, including EPA, DHA and GLA, support the composition of the lipid, aqueous and mucin layers that comprise the tear film, the coating of fluid that covers the eye. They also support healthy prostaglandin and cytokine production to promote inflammatory balance and eye comfort.8*

The vast amount of clinical data collected over the past decade has shed light on the critical importance of these specific nutrients for vision and eye health. Estimates suggest 8 million people over the age of 55 are concerned with eye health and this number is only expected to increase. Antioxidants, carotenoids, minerals and essential fatty acids offer targeted support for these individuals.*

* FDA REQUIRED STATEMENT: Statements on this site have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure, or prevent any disease.

References:

  1. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol. 2001 Oct;119(10):1417-36.
  2. Parekh N, Chappell RJ, Millen AE, Albert DM, Mares JA. Association between vitamin D and age-related macular degeneration in the Third National Health and Nutrition Examination Survey, 1988 through 1994. Arch Ophthalmol. 2007 May;125(5):661-9.
  3. SanGiovanni JP, Chew EY, Agrón E, et al. The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol. 2008 Sep;126(9):1274-9.
  4. Mares JA, LaRowe TL, Snodderly DM, et al. Predictors of optical density of lutein and zeaxanthin in retinas of older women in the Carotenoids in Age-Related Eye Disease Study, an ancillary study of the Women's Health Initiative. Am J Clin Nutr. 2006 Nov;84(5):1107-22.
  5. Rodriguez-Carmona M, Kvansakul J, et al. The effects of supplementation with lutein and/or zeaxanthin on human macular pigment density and colour vision. Ophthalmic Physiol Opt. 2006 Mar;26(2):137-47.
  6. Richer S, Stiles W, Statkute L, et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 2004 Apr;75(4):216-30.
  7. Miljanovic B, Trivedi KA, Dana MR, et al. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr. 2005 Oct;82(4):887-93.
  8. Rosenberg ES, Asbell PA. Essential fatty acids in the treatment of dry eye. Ocul Surf. 2010 Jan;8(1):18-28.

 
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